Why Hiring a Depo-Provera Lawsuit Attorney Could Change Everything

A Depo-Provera lawsuit attorney can help you pursue compensation from Pfizer if you used Depo-Provera and were later diagnosed with a meningioma brain tumor.

Here’s what you need to know right now:

• Who qualifies: Women who received at least two Depo-Provera injections and were diagnosed with a meningioma
• Who to sue: Pfizer Inc. and related manufacturers for failure to warn about brain tumor risks
• Where cases are filed: MDL No. 3140, Northern District of Florida
• How much cases may be worth: Estimated $275,000 to $1.5 million+ depending on severity
• What it costs you upfront: Nothing — attorneys work on contingency (no win, no fee)
• How to start: Contact a Depo-Provera lawsuit attorney for a free case evaluation

Over 1,775 cases are already pending in federal court as of January 2026. A landmark 2024 study published in The BMJ found that women who used Depo-Provera for more than one year face a 5.6-fold increased risk of developing a meningioma. Yet for years, Pfizer’s U.S. label said nothing about this risk — even as warnings appeared in Europe and Ireland.

If you used Depo-Provera and received a meningioma diagnosis, you are not alone. And you may have a strong legal claim.

I’m Mason Arnao, and while my background is in data systems and internet marketing, I’ve spent years helping connect people with the right legal resources — including researching emerging mass tort litigation like Depo-Provera lawsuit attorney cases. This guide will walk you through everything you need to make an informed decision, quickly and clearly.

Depo-Provera lawsuit attorney vocab to learn:

• Depo-Provera lawsuit eligibility
• Depo-Provera lawsuit settlements
• Depo-Provera severe side effects

Understanding the Link Between Depo-Provera and Meningioma Brain Tumors

To understand why so many women are seeking a Depo-Provera lawsuit attorney, we have to look at the science. Depo-Provera is an injectable contraceptive that uses a synthetic hormone called medroxyprogesterone acetate (MPA). It’s incredibly popular; statistics show that nearly 24.5% of sexually experienced U.S. women used this “birth control shot” at some point between 2015 and 2019.

However, recent studies have sounded a major alarm. A March 2024 report in the British Medical Journal (BMJ) revealed that long-term use of Depo-Provera (defined as more than one year) increases the risk of developing an intracranial meningioma by 5.6 times.

What Exactly is a Meningioma?

A meningioma is a tumor that forms in the protective membranes (meninges) that cover the brain and spinal cord. While they are often non-cancerous (benign), they are far from harmless. Because they grow inside the skull, they can press against brain tissue, nerves, and vessels, causing life-altering disabilities.

The connection isn’t actually “new” to the scientific community. As far back as 1983, a study published in the European Journal of Cancer & Clinical Oncology identified a high concentration of progesterone receptors in human meningioma cells. Since Depo-Provera is a progestogen, it essentially “feeds” these hormone-sensitive cells, potentially triggering tumor growth.

If you have used the shot, it is vital to stay vigilant. You can find more info about Depo-Provera brain tumor symptoms here, but common signs include persistent headaches, vision changes, and seizures.

Why You Need a Depo-Provera Lawsuit Attorney for Your Claim

Filing a claim against a pharmaceutical giant like Pfizer isn’t like filing a standard insurance claim. It is a complex battle of “failure to warn.” Plaintiffs allege that Pfizer knew—or should have known—about the brain tumor risks for decades but chose to keep the U.S. label clean of any warnings to protect their profits.

A specialized Depo-Provera lawsuit attorney provides the “firepower” needed for these cases. You can find more info about the Depo-Provera injury claim process to see how these steps work, but generally, an attorney handles the heavy lifting:

• Proving Causation: Linking your specific tumor to your specific history of Depo-Provera use.
• Expert Testimony: Hiring neurologists and oncologists to explain the science to a jury.
• Discovery: Forcing Pfizer to hand over internal documents and emails regarding what they knew about meningioma risks.

The legal landscape changed even more with a new Cleveland Clinic study in JAMA Neurology, which looked at over 10 million women and confirmed that long-term users—especially those starting after age 31—face a significantly higher risk.

How a Depo-Provera Lawsuit Attorney Navigates the MDL

You might hear the term “class action,” but the Depo-Provera litigation is actually a Multidistrict Litigation (MDL). In February 2025, the Judicial Panel on Multidistrict Litigation ordered the consolidation of federal lawsuits into MDL No. 3140.

This MDL is based in the Northern District of Florida under Judge M. Casey Rodgers. An MDL is beneficial because it streamlines the “discovery” phase (gathering evidence) so it doesn’t have to be done 1,775 times. However, your case remains individual, meaning your settlement is based on your specific injuries. For the latest on where things stand, check more info about the legal status of Depo-Provera lawsuits.

The Advantage of Hiring a Depo-Provera Lawsuit Attorney for Evidence Gathering

One of the biggest hurdles for women who used the shot years ago is finding proof. Maybe your old clinic closed, or your pharmacy changed systems. A Depo-Provera lawsuit attorney has investigators who specialize in tracking down:

• Pharmacy Records: Proving you received medroxyprogesterone acetate.
• Medical History: Documenting the date of your meningioma diagnosis.
• Insurance Records: Showing billing for the injections.

Most firms use a system called BrownGreer MDL Centrality to manage these documents securely. To see if your history fits the current legal criteria, you can find more info about lawsuit qualifications on our site.

Eligibility and Evidence: Do You Have a Case Against Pfizer?

To qualify for a Depo-Provera brain tumor claim, attorneys generally look for a few “minimum” criteria. While every case is unique, the current standard for a strong claim includes:

1. Proof of Use: You must have received at least two injections of Depo-Provera (or its authorized generic).
2. Diagnosis: A confirmed diagnosis of an intracranial meningioma (or other brain tumor).
3. Timing: The tumor must have been diagnosed after you started using the shot.

It is important to act quickly. Every state has a “statute of limitations”—a deadline to file. However, because the link between the shot and brain tumors was only recently made public (March 2024), the “discovery rule” may extend your deadline. This rule essentially says the clock doesn’t start until you could have known the drug caused your injury. Check more info about Depo-Provera lawsuit eligibility for state-specific details.

Current Status of Depo-Provera MDL and Settlement Projections

As of early 2026, the litigation is moving at a rapid pace. There are currently 1,775 pending cases in the MDL, and plaintiffs’ lawyers report holding nearly 10,000 additional unfiled claims.

While no mass settlement has been reached yet, legal experts are looking at “predicted settlement tiers.” Based on previous meningioma lawsuits and the severity of brain surgery, more info about Depo-Provera settlement amounts suggests the following estimates:

• High-Tier Claims ($500,000 – $1.5M+): Cases involving Grade II or III tumors, multiple brain surgeries (craniotomies), or permanent cognitive/physical disability.
• Mid-Tier Claims ($275,000 – $500,000): Cases involving Grade I tumors that required surgery and resulted in significant medical bills and lost wages.
• Lower-Tier Claims ($100,000 – $275,000): Cases where the tumor is small or asymptomatic but requires lifelong “watch and wait” monitoring with expensive MRIs.

Pfizer is currently fighting these claims using a “preemption” defense, arguing that because the FDA approved the drug, they shouldn’t be liable for state-level failure-to-warn claims. However, a new safety study from the University of British Columbia has given plaintiffs additional momentum by confirming the 3.55-fold to 5.6-fold risk increase.

Frequently Asked Questions about Depo-Provera Brain Tumor Claims

Has Depo-Provera been recalled by the FDA?

No, Depo-Provera has not been recalled. It remains on the market as an FDA-approved contraceptive. However, its history is full of warnings. In 2004, the FDA issued a “Black Box Warning” regarding bone mineral density loss, advising that the shot should not be used for more than two years. It wasn’t until December 2025 that the FDA finally approved a label update to include the risk of brain tumors. You can read more info about severe side effects here.

What are the primary symptoms of a Depo-Provera-linked meningioma?

Many meningiomas grow slowly, but as they increase in size, they can cause:

• Blurred or double vision
• New or worsening seizures
• Persistent, severe headaches
• Memory loss or confusion
• Loss of hearing or smell
• Weakness in the arms or legs

If you experience these, see a doctor immediately. For a full list, see more info about brain tumor symptoms.

Who are the main defendants in these lawsuits?

The primary defendant is Pfizer Inc., as they are the main manufacturer. Other defendants include Pharmacia & Upjohn Company (a Pfizer subsidiary), Viatris (which handles some older Pfizer products), and various generic manufacturers of medroxyprogesterone acetate.

Conclusion

We believe that no woman should have to choose between effective birth control and her long-term neurological health. Pfizer had the data, they saw the studies, and they updated their labels in Europe—yet they left American women in the dark for years.

At Tort Advisor, we connect you with a Depo-Provera lawsuit attorney who has the experience and resources to take on big pharma. We work exclusively with highly skilled attorneys who have a proven track record of results—recovering over $11.7 billion for clients in dangerous drug cases.

If you or a loved one were diagnosed with a meningioma after using the Depo shot, don’t wait. Consultations are 100% free, and we charge no fees unless we win your case. You can find more info about filing a Depo-Provera lawsuit and start your journey toward justice today.